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Borne1,6Top of pageAbstractIn the REAL classification the diffuse large Bcell nonHodgkin lymphomas (NHL) are grouped together, because subclassifications are considered to lack both NFL Hats reproducibility and clinical significance. Others, however, claim that patients with an immunoblastic NHL have a worse prognosis than patients with other types of diffuse large Bcell NHL. Therefore, we investigated the prognostic and clinical significance of histological subclassification of diffuse large Bcell NHL in a uniformly treated series of patients.

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